China Swine Industry ›› 2021, Vol. 16 ›› Issue (6): 63-66.doi: 10.16174/j.issn.1673-4645.2021.06.014

• Husbandry and Forage • Previous Articles     Next Articles

Evaluation Test of Digestive Tract Absorption and Utilization of Swines with Tilmicosin Premix of Different Processes

Keanpen, LIU Jigen, ZHAO Yiyi, WEN Huaxin, LUO Chang   

  1. 1Dogain Biosciences, America;
    2Changsha Dogain Biosciences Co., Ltd, Changsha 410125, China
  • Received:2021-10-12 Online:2021-12-25 Published:2022-01-18

PDF (PC)

99

Abstract: In order to evaluated the effects of four different premixes of Tilmicosin on the absorption and utilization rate of swines' digestive tract, the analysis was conducted on the feed intake and plasma concentration results of 20 healthy ternary grocery pigs weighing about 40 kg. The results showed that, compared with the other three premix products of Tilmicosin technology, the "Xingyue technology" tilmicosin product did not affect the feed intake, and played a slow-release effect of the drug in the swine body, which reduced the drug's effect. Stomach irritation and gastric acid affected the efficacy of the drug, and the concentration of the drug in the blood was high and the efficacy lasts longer.

Key words: Tilmicosin, swine, palatability, pharmacokinetics, plasma concentration

CLC Number: 

  • S828
[1] Shen J, Li C, Jiang H, et al.Pharmacokinetics of tilmicosin after oral administration in swine[J]. American Journal of Veterinary Research, 2005, 66(6):1071-1074.
[2] 操继跃. 兽医药理学与治疗学[M]. 北京: 中国农业出版社, 2012.
[3] 李启芳. “替米考星”在兽医临床中的应用[J]. 农业开发与装备, 2015(9):147.
[4] 宋福杰, 刘明春, 符特.替米考星的应用研究进展[J]. 现代畜牧兽医, 2006(7):63-65.
[5] 赵林. 替米考星在生猪生产上的应用[J]. 中国猪业, 2012, 7(5):60.
[6] 王玉, 付宝明, 常靖, 等. 替米考星对猪蓝耳病防控的研究进展[J]. 中国猪业, 2017, 12(10):53-55.
[7] Lin C, Yang Y, Lin W, et al.Tilmicosin reduces PRRSV loads in pigs in vivo[J]. Journal of Agricultural Science, 2015, 8(1):154.
[8] 远立国. 替米考星微球药效学试验[J]. 养殖技术顾问, 2009(6):148.
[9] Rassouli A, Al-qushawi A, Atyabi F, et al. Pharmacokinetics and bioavailability of three promising tilmicosin-loaded lipid nan-oparticles in comparison with tilmicosin phosphate following oral administration in broiler chickens[J]. Turkish Journal of Veterinary and Animal Sciences, 2016, 40(5):540-547.
[10] 封琦. 替米考星在猪体内的药代动力学研究[J]. 中国兽药杂志, 2019(4):59-64.
[1] TAN Ying, ZENG Fang, LI Dasheng. The Development of Hog Industry in the Context of Environmental Regulation and African Swine Fever: Practice Investigation and Case Study [J]. China Swine Industry, 2021, 16(3): 13-18.
[2] SUN Qiongfei, WANG Ziyang, ZHANG Xiaoyu, DANG Ruiying, CHANG Junshuai, QU Yonggang, LI Yan. Detection and Analysis of Antibodies Against Classical Swine Fever Virus in Xinjiang in 2020 [J]. China Swine Industry, 2021, 16(2): 56-58.
Viewed
Full text


Abstract

Cited
  Shared   
  Discussed   
No Suggested Reading articles found!
Copyright © 2018 Editorial Board of China Swine Industry
Powered by Beijing Magtech Co. Ltd