Abstract: This article provided a comprehensive introduction to needle-free injection technology, covering its development history, working principle, differences from traditional injection methods, practical applications, and facing challenges in the future. With the continuous development of the needle-free injection technology, as a new delivery drug method, it was gradually used to animal immunization. The needle-free injection technology could reduce the immunization cost significantly and have remarkable advantages in improving animal welfare. However, practical issued such as high equipment costs, insufficient adaptability to oil adjuvant vaccines, limited injection efficiency, and difficulties in determining the success or failure still restricted its large-scale application. The article had a depth discussion in needle-free injection technology, It aimed to provide a theoretical basis for its further development and optimization in terms of technical principles, jet parameters, and the collaborative innovation of vaccines and equipment, so as to promote its popularization in relevant fields.

Key words: pig farm; livestock and poultry; needle-free injection technology; immunization practice; traditional injection; challenges