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China Swine Industry    2026, 21 (2): 4-12.   DOI: 10.16174/j.issn.1673-4645.2026.02.001 Abstract （513）      PDF（pc） （1743KB）（79）       Knowledge map    Save Porcine reproductive and respiratory syndrome virus (PRRSV) poses a serious threat to the healthy development of the global swine industry. The virus is of extensive genetic heterogeneity, with successive emergence of divergent lineages in China—including GM2-like, NADC30-like and NADC34-like strains, following the initial outbreak of highly pathogenic PRRSV. The concurrent circulation of multiple lineage strains has facilitated frequent viral recombination events. Several recombinant variants exhibit expanded cellular tropism and heightened virulence in pigs. Moreover, recombination-driven antigenic variation can compromise diagnostic specificity and diminish vaccine-induced immunity. Consequently, recombinant PRRSV strains have emerged as a critical challenge in disease surveillance, diagnosis, and control. This review synthesized recent research on PRRSV recombination, with emphasis on the genomic architecture, spatiotemporal distribution, and molecular determinants of recombination events; their phenotypic consequences, including impacts on viral fitness, host range, pathogenicity and current hypotheses regarding underlying recombination mechanisms. By consolidating these advances, this review aimed to inform strategies for mitigating recombination risk, elucidate fundamental molecular pathways governing recombination, accelerate the development of broadly protective vaccines, and enable precision interventions for PRRS management. Related Articles | Metrics | Comments（0）

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China Swine Industry    2026, 21 (2): 13-22.   DOI: 10.16174/j.issn.1673-4645.2026.02.002 Abstract （338）      PDF（pc） （1802KB）（11）       Knowledge map    Save Porcine reproductive and respiratory syndrome virus (PRRSV) remains one of the most consequential pathogens threatening the sustainable development of the global swine industry. Its high genetic variability, capacity for persistent infection, and pronounced immune evasion continue to undermine the effectiveness of existing vaccines and conventional biosecurity-based control measures. As insight into host-virus interactions has deepened, host-directed strategies based on the identification of resistance genes have emerged as an increasingly important direction in PRRS research. In recent years, leveraging technologies such as transcriptomics, proteomics, genome-wide association analysis, RNA interference and CRISPR-based genome editing have enabled the identification of a growing set of key host factors involved in receptor recognition, viral entry, replication control and innate immune responses. Studies involving CD163, including whole-gene knockout, deletion of key domains, precise exon editing, and site-specific substitution, have demonstrated that genetically edited pigs expressing CD163 exhibit a relatively stable phenotype of resistance to PRRSV infection, thereby providing a new technical approach for disease-resistant breeding in pigs. Here we systematically reviewed recent strategies for identifying PRRSV host resistance genes and the major advances in this field, with a particular focus on the status, antiviral efficacy and translational prospects of CD163-edited pigs. We also discussed the challenges that remain, including biological safety, genetic stability and the potential for viral adaptive evolution, with the aim of informing future work on PRRS control and disease-resistant breeding. Related Articles | Metrics | Comments（0）

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China Swine Industry    2026, 21 (1): 20-28.   DOI: 10.16174/j.issn.1673-4645.2026.01.004 Abstract （761）      PDF（pc） （2276KB）（29）       Knowledge map    Save In recent years, with global warming and the frequent occurrence of extreme weather events, mold infections in crops and livestock feed have become increasingly severe. Mycotoxins are toxic metabolites produced by molds during their growth, which widely contaminate agricultural products and animal feed and exert strong toxic effects. Among livestock, pigs are the most sensitive to mycotoxins. When pigs ingest feed contaminated with different mycotoxins, they can suffer multi-system damage, including to the digestive, immune, and reproductive systems. One of the most typical and common clinical symptoms is anorexia or food refusal in pigs, which seriously affects their growth performance. Pig appetite is regulated by multiple factors. Different mycotoxins cause varying types of damage to pigs and suppress their appetite through different pathways. This article provided a comprehensive review of the regulatory mechanisms and potential hazards of different mycotoxins in pigs, aimed to explore the differences and commonalities among them, offer new breakthroughs for the prevention and control of mycotoxins, and provide reference for healthy livestock farming and the development of related products. Related Articles | Metrics | Comments（0）

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China Swine Industry    2026, 21 (1): 40-55.   DOI: 10.16174/j.issn.1673-4645.2026.01.006 Abstract （616）      PDF（pc） （2027KB）（10）       Knowledge map    Save Bacterial extracellular vesicles (BEVs) are nano-scale membrane-enclosed structures actively secreted by all bacteria, with a diameter ranging from 20～400 nm. They carry various bioactive molecules such as proteins, nucleic acids, and lipids, and play a key role in bacterial physiological activities and host interactions. With the integration of veterinary medicine and nanobiology, research on BEVs in the field of swine disease prevention and control is increasingly in-depth. This article systematically reviewed the biological characteristics of bacterial extracellular vesicles, compared the functional differences between BEVs derived from Gram-positive and Gram-negative bacteria, analyzed their composition and interaction mechanisms with the host, emphatically elaborated on the application practices and mechanisms of action of BEVs in postweaning diarrhea in piglets, further looked forward to their industrial application potential, aiming to provide a theoretical reference for the development of precise prevention and control technologies for postweaning diarrhea in piglets. Related Articles | Metrics | Comments（0）

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China Swine Industry    2025, 20 (6): 3-11.   DOI: 10.16174/j.issn.1673-4645.2025.06.001 Abstract （1526）      PDF（pc） （3261KB）（28）       Knowledge map    Save Sex control technology is a core technique for optimizing the breeding system and enhancing breeding efficiency, which is great significance to the high-quality development of the pig industry. Among them, the efficient separation technology of X/Y sperm is the core link of pig sex control technology. This article focused on the research progress of the formation process, differential characteristics and separation techniques of X/Y sperm in pigs, and deeply analyzed the bottlenecks of current sorting technologies in terms of efficiency, safety and industrial application. Although high-purity separation can already be achieved by using flow cytometry sorting technology, there are still problems such as high cost, viability damage great and difficulty in industrial application. Emerging technologies such as microfluidic chips and immune sorting techniques have the potential for low damage, but they still need to be further verified in production. In the future, it is necessary to strengthen basic research in this field, analyze key molecular markers, develop low-cost, efficient, safe and portable sorting technologies, promote the integrated application of multiple technologies, so as to break through the difficulties in industrial application and contribute to the construction of an efficient pig breeding system and the high-quality development of the industry. Related Articles | Metrics | Comments（0）

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China Swine Industry    2025, 20 (6): 12-24.   DOI: 10.16174/j.issn.1673-4645.2025.06.002 Abstract （1466）      PDF（pc） （6576KB）（53）       Knowledge map    Save As a member of the transforming growth factor-β (TGF-β) superfamily, myostatin (MSTN) plays a critical role in regulating skeletal muscle development and lipid deposition. Due to the rapid advancement of gene editing technology and the need for high production performance in practical applications, a growing number of studies have carried out MSTN knockout in different pig breeds. This review summarized the important function of MSTN in breeding and systematically analyzed the phenotypic outcomes of MSTN-knockout pigs, including muscle development, carcass traits, fat deposition, and meat quality. Overall, MSTN-knockout pigs generally exhibit higher lean meat yield, lower fat content, improved tenderness, and enhanced nutritional profiles—particularly in terms of polyunsaturated fatty acids and amino acids. At the molecular level, MSTN knockout activates the PI3K/AKT/mTOR pathway to promote protein synthesis and modulates lipid metabolism via the ERK1/2 signaling pathway, thereby significantly improving meat quality and metabolic characteristics. In conclusion, obtaining a deeper understanding of the role and mechanisms of MSTN is crucial for animal breeding and provides promising strategies to enhance meat production in livestock. Related Articles | Metrics | Comments（0）

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China Swine Industry    2025, 20 (4): 3-11.   DOI: 10.16174/j.issn.1673-4645.2025.04.001 Abstract （931）      PDF（pc） （2024KB）（46）       Knowledge map    Save Corn served as the primary energy feed source, yet domestic supplied remains heavily import-dependent. In 2024, China led global corn imports with 13.64 million metric tons. Recent years had seen rising production costs for corn-based feed due to policy changing and other factors. Finding corn alternatives was critical to develop intensive and sustainable operations in China's swine industry. Research showed cyperus esculentus, vegetable waste (vegetable processing residues), fruit pomace, and cassava worked well as alternative energy feeds. Studying their nutrition, metabolism, and effects on intestinal microbiota and gut barriers would help improve their use as replacements. This review examined the nutritional value of Cyperus esculentus, vegetable waste (vegetable processing residues), fruit pomace, and cassava, focused on how they affect intestinal microbiota. The goal was to support better feed solutions and sustainable growth in China's swine and feed industries. Related Articles | Metrics | Comments（0）

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China Swine Industry    2025, 20 (4): 12-23.   DOI: 10.16174/j.issn.1673-4645.2025.04.002 Abstract （1033）      PDF（pc） （5958KB）（70）       Knowledge map    Save With the rapid development of my country's pig farming industry, the shortage of corn as the main energy feed had become increasingly prominent, and had become a key factor restricting feed grain safety and breeding cost control. In order to alleviate the structural contradiction of feed grain and promote the diversification of feed resources, this paper systematically sorted out the types of energy feed resources that could be used to replace corn in my country and their feeding research progress. The nutritional composition, metabolic energy level, anti-nutritional factor characteristics of tubers such as rice, wheat, sorghum, barley, cassava, potato, sweet potato, and sugar products such as molasses and near-expiry candy were analyzed, as well as their applicability in different pig breeds and feeding stages. The results showed that a variety of alternative resources had certain advantages in nutritional structure, regional production capacity and feeding function, and could achieve effective partial replacement of corn on the basis of scientific formula and reasonable processing. However, the current alternative resources still faced problems such as ingredient fluctuations, poor processing adaptability and imperfect supply chain system in the industrial application of feed. In order to promote its large-scale promotion and application, it was necessary to strengthen the construction of nutritional standard system, optimization of processing detoxification technology, construction of resource dynamic database and integration of regional industrial chain in the future. This study provided a theoretical basis and technical support for the optimization of pig feed structure and efficient development of alternative resources in my country. Related Articles | Metrics | Comments（0）

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China Swine Industry    2025, 20 (3): 3-15.   DOI: 10.16174/j.issn.1673-4645.2025.03.0001 Abstract （846）      PDF（pc） （1451KB）（30）       Knowledge map    Save The Dahe pigs were one of the important groups of the Wujin pigs, as a typical representative of meat-fat type pig breeds, they were a local breed in Southwest China, and had been included in the national genetic resources protection list and had become a national protected pig breed. The Dahe pig was famous for its large body size, strong resistance, tolerance to rough feeding, high intramuscular fat content, and tender, delicious meat quality. It was one of the three famous national hams, the "Yun ham" and the preferred raw material of "Yun ham" pig breed. Extensive and systematic research had been conducted around the conservation and breeding, crossbreeding utilization, meat quality characteristics, genetic diversity, and molecular breeding of the Dahe pig. These studies were of great significance and value for the protection and development of the Dahe pig's germplasm resources. This article aimed to summarize the achievements of germplasm resources of past 50 years, in the hope of providing a reference for the in-depth conservation of breeding and development of the Dahe pig, and promoting the high-quality and sustainable development of the Dahe pig industry. Related Articles | Metrics | Comments（0）

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China Swine Industry    2025, 20 (3): 16-22.   DOI: 10.16174/j.issn.1673-4645.2025.03.002 Abstract （1155）      PDF（pc） （1266KB）（9）       Knowledge map    Save To investigate the reproductive performance of XS3 line sows and the parental generation sows of Xiangsha pig commercial lines, some reproductive performance data of Xiangsha pig commercial lines breeding farm from 2018 to 2023 were selected. After analysis, it was found that: ⑴ Under the pure breeding model, among the XS3 line sows in parity 1 to 7, the reproductive performance was optimal in parity 4 to 7. ⑵ Under the hybrid model, when the mating boars were Yorkshire or Landrace pigs, the reproductive performance of XS3 line sows were significantly better than when the mating boars were Berkshire pigs. ⑶ Among the parental generation sows of Xiangsha pig commercial lines in parity 1 to 4, the reproductive performance was optimal in the 4th parity. In summary, parity had a significant impact on the reproductive performance of the XS3 line sows and the parental generation sows of Xiangsha pig commercial lines, and different breeds of boars also had a significant impact on the reproductive performance of the XS3 line sows. It provided data basis for the continuous breeding of Xiangsha pig breeding lines. Related Articles | Metrics | Comments（0）

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China Swine Industry    2025, 20 (2): 5-14.   DOI: 10.16174/j.issn.1673-4645.2025.03.001 Abstract （2127）      PDF（pc） （1639KB）（629）       Knowledge map    Save Xenotransplantation had attracted much attention as a potential solution to the global organ shortage problem, with gene-edited pigs receiving even more attention as a source of donors. In contrasted to the numerous challenges faced in traditional or gan transplantation, when porcine organs were transplanted into humans, they primarily encounter issued such as immune rejection, coagulation dysfunction, and organ size mismatch. Gene-editing technologies like CRISPR/Cas9 could precisely target relevant gene loci in pigs, enabling targeted improvements in aspects such as the knockout of immunogenic antigens (e.g., knockout of the GGTA1 gene), inhibition of complement activation (e.g., inhibition of the β2M gene), regulation of coagulation function (e.g., regulation of the vWF gene), and control of organ growth (e.g., control of the GHR gene), thereby specifically addressing the problems associated with porcine organ transplantation. Additionally, the introduction of human transgenes(e.g., the hCD47 gene) could further enhance the immune toler ance of porcine organs. Globally, multiple subclinical and clinical studied on the transplantation of genetically edited pig kidneys and livers into humans had been successfully conducted, yielding remarkable progress. However, due to the wide variety of gene-editing tools, there were differences in their mechanisms of action and safety, presenting certain technical and safety thresholds. Therefore, this paper systematically summarized the key genes that need to be edited in donor pigs for xenotransplantation that had entered subclinical and clinical trials and the specific editing methods. It also explored and analyzed the safety and efficiency issues of gene-editing tools, as well as the current opportunities and challenges. On the premise of ensuring the safety and effectiveness of gene editing, this paper aimed to provide some references for optimizing relevant gene-editing methods and promoting subsequent research, so as to advance xenotransplantation technology to a new level. Reference | Related Articles | Metrics | Comments（0）

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China Swine Industry    2025, 20 (2): 15-22.   DOI: 10.16174/j.issn.1673-4645.2025.02.002 Abstract （1454）      PDF（pc） （1545KB）（163）       Knowledge map    Save Gene editing technology had demonstrated significant potential in the genetic improvement of pigs and biomedical research. Gene-edited pigs exhibited good production traits and disease resistance, which could increase breeding income. Due to their closer resemblance to humans in anatomical structure, metabolism, and physiological-biochemical characteristics compared to rodents, pigs served as ideal disease models and xenotransplantation organ donors. However, gene-edited pigs also faced multiple challenges, including the need to improve the efficiency and accuracy of gene editing, as well as addressing off-target effects that might lead to unintended genetic alterations. Additionally, divergent regulatory policies across regions pose obstacled to the industrialization and commercialization of gene-edited pigs. A comprehensive understanding of the current status and challenges of gene-edited pigs would facilitate their rational development in scientific research and practical applications. Reference | Related Articles | Metrics | Comments（0）

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China Swine Industry    2025, 20 (1): 3-11.   DOI: 10.16174/j.issn.1673-4645.2025.01.001 Abstract （1675）      PDF（pc） （1635KB）（687）       Knowledge map    Save Reference | Related Articles | Metrics | Comments（0）

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China Swine Industry    2025, 20 (1): 35-46.   DOI: 10.16174/j.issn.1673-4645.2025.01.004 Abstract （1361）      PDF（pc） （1650KB）（136）       Knowledge map    Save Reference | Related Articles | Metrics | Comments（0）

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China Swine Industry    0, (): 11-2.   Abstract （118）      PDF（pc） （529KB）（6）       Knowledge map    Save Related Articles | Metrics | Comments（0）

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China Swine Industry    2024, 19 (6): 3-13.   DOI: 10.16174/j.issn.1673-4645.2024.06.004 Abstract （980）      PDF（pc） （4134KB）（546）       Knowledge map    Save Related Articles | Metrics | Comments（0）

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China Swine Industry    2024, 19 (6): 14-25.   DOI: 10.16174/j.issn.1673-4645.2024.06.005 Abstract （1545）      PDF（pc） （2424KB）（53）       Knowledge map    Save Related Articles | Metrics | Comments（0）

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China Swine Industry    2024, 19 (5): 3-10.   DOI: 10.16174/j.issn.1673-4645.2024.05.001 Abstract （1906）      PDF（pc） （1526KB）（332）       Knowledge map    Save Related Articles | Metrics | Comments（0）

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China Swine Industry    2024, 19 (5): 11-21.   DOI: 10.16174/j.issn.1673-4645.2024.05.002 Abstract （2006）      PDF（pc） （1765KB）（372）       Knowledge map    Save Related Articles | Metrics | Comments（0）

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China Swine Industry    2024, 19 (1): 63-72.   DOI: 10.16174/j.issn.1673-4645.2024.01.010 Abstract （873）      PDF（pc） （2064KB）（165）       Knowledge map    Save Reference | Related Articles | Metrics | Comments（0）

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China Swine Industry    2024, 19 (1): 73-83.   DOI: 10.16174/j.issn.1673-4645.2024.01.011 Abstract （934）      PDF（pc） （33364KB）（98）       Knowledge map    Save Reference | Related Articles | Metrics | Comments（0）

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China Swine Industry    2024, 19 (1): 84-89.   DOI: 10.16174/j.issn.1673-4645.2024.01.012 Abstract （892）      PDF（pc） （2481KB）（118）       Knowledge map    Save Reference | Related Articles | Metrics | Comments（0）

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China Swine Industry    2024, 19 (1): 90-94.   DOI: 10.16174/j.issn.1673-4645.2024.01.013 Abstract （1370）      PDF（pc） （1527KB）（220）       Knowledge map    Save Reference | Related Articles | Metrics | Comments（0）

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China Swine Industry    2023, 18 (6): 13-18.   DOI: 10.16174/j.issn.1673-4645.2023.06.002 Abstract （843）      PDF（pc） （2247KB）（154）       Knowledge map    Save Reference | Related Articles | Metrics | Comments（0）

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China Swine Industry    2023, 18 (6): 19-22.   DOI: 10.16174/j.issn.1673-4645.2023.06.003 Abstract （1072）      PDF（pc） （1590KB）（179）       Knowledge map    Save Reference | Related Articles | Metrics | Comments（0）

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China Swine Industry    2023, 18 (6): 42-45.   DOI: 10.16174/j.issn.1673-4645.2023.06.007 Abstract （1021）      PDF（pc） （1528KB）（271）       Knowledge map    Save Reference | Related Articles | Metrics | Comments（0）

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China Swine Industry    2023, 18 (6): 67-69.   DOI: 10.16174/j.issn.1673-4645.2023.06.014 Abstract （998）      PDF（pc） （1599KB）（53）       Knowledge map    Save Reference | Related Articles | Metrics | Comments（0）

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China Swine Industry    2023, 18 (6): 73-81.   DOI: 10.16174/j.issn.1673-4645.2023.06.016 Abstract （737）      PDF（pc） （1827KB）（113）       Knowledge map    Save Reference | Related Articles | Metrics | Comments（0）

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China Swine Industry    2023, 18 (6): 82-86.   DOI: 10.16174/j.issn.1673-4645.2023.06.017 Abstract （954）      PDF（pc） （1690KB）（213）       Knowledge map    Save Reference | Related Articles | Metrics | Comments（0）

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China Swine Industry    2023, 18 (6): 135-137,141.   DOI: 10.16174/j.issn.1673-4645.2023.06.030 Abstract （738）      PDF（pc） （2962KB）（72）       Knowledge map    Save Reference | Related Articles | Metrics | Comments（0）

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China Swine Industry    2023, 18 (6): 138-141.   DOI: 10.16174/j.issn.1673-4645.2023.06.031 Abstract （800）      PDF（pc） （1775KB）（49）       Knowledge map    Save Reference | Related Articles | Metrics | Comments（0）

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China Swine Industry    2023, 18 (6): 142-145.   DOI: 10.16174/j.issn.1673-4645.2023.06.032 Abstract （826）      PDF（pc） （1776KB）（35）       Knowledge map    Save Reference | Related Articles | Metrics | Comments（0）

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China Swine Industry    2023, 18 (6): 161-165.   DOI: 10.16174/j.issn.1673-4645.2023.06.037 Abstract （544）      PDF（pc） （1813KB）（74）       Knowledge map    Save Reference | Related Articles | Metrics | Comments（0）

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China Swine Industry    2009, 4 (S1): 4-7.   Abstract （284）      PDF（pc） （2035KB）（81）       Knowledge map    Save Related Articles | Metrics | Comments（0）