Abstract: In present, ASF vaccine, mutant, and wild viruses coexist. It was no sufficient to prevention and control the ASF disease by only doing external biological security. Because the vaccine virus is highly concealed and difficult to detect, it didn't know whether the introduction would brought the vaccine virus to the pig farm. Therefore, pig farm biosecurity should not only focus on off-site biosecurity in the future, but more importantly, it was necessary to use the pig-based "1237" P biosafety three-dimensional ASF prevention and control system. That is, while controlling external biosecurity such as "control five streams", paying more attention to the safety of drinking water, the health of the pigs, and the improvement of the ASF immunity of the pigs in order to achieve "coexistence with ASF and dance with PRRS". The "three-dimensional prevention and control" refers to prevention and control exhaustive. It was not just the traditional biological safety prevention and control of the pig farm gate.

Key words: P biosafety, "controlling the five streaming", thorough disinfection, ASF